BACKED BY PUBLISHED SCIENCE

Brain Sentinel’s SPEAC® System and the use of sEMG as a clinical biomarker has been studied and researched for years. Interest in the topic has been increasing as the sEMG’s value as a useful biomarker has been recognized. Here is a sample of what has been published to date:

SPEAC® System Published Clinical Research

    1. Cardenas, Damon P.; Halford, Jonathan J.; Whitmire, Luke E.; Morgan, Lola C.; Lie, Octavian V.; Jetter, Gina M.; Cavazos, Jose E., Automated Processing of Single-Channel Surface Electromyography From Generalized Tonic–Clonic Seizures to Inform Semiology. Journal of Clinical Neurophysiology: July 22, 2019. doi: 10.1097 
      Click to view or download the full article.

    2. Halford, J. J., Sperling, M. R., Nair, D. R., Dlugos, D. J., Tatum, W. O., Harvey, J., French, J. A., Pollard, J. R., Faught, E., Noe, K. H., Henry, T. R., Jetter, G. M., Lie, O. V., Morgan, L. C., Girouard, M. R., Cardenas, D. P., Whitmire, L. E. and Cavazos, J. E. (2017), Detection of generalized tonic–clonic seizures using surface electromyographic monitoring. Epilepsia. doi:10.1111/epi.13897. 
      Click to view or download the full article.

    3. Szabó, C. Á., Morgan, L. C., Karkar, K. M., Leary, L. D., Lie, O. V., Girouard, M. and Cavazos, J. E. (2015), Electromyography-based seizure detector: Preliminary results comparing a generalized tonic–clonic seizure detection algorithm to video-EEG recordings. Epilepsia, 56: 1432–1437. Doi:10.1111/epi.13083. 
      Click to view or download the full article.

SPEAC® System Posters & Presentations

2019 POSTER PRESENTATIONS

AAN 2019

Diagnostic utility of continuous sEMG monitoring in a home setting (real-world use of the SPEAC® System).

AAN 2019

Surface electromyography (sEMG) burst patterns during GTC Seizures.

2018 POSTER PRESENTATIONS

AAN 2018

Evaluation of quality and safety measure in the Epilepsy Monitoring Unit.

AAN 2018

Surface EMG from the Brain Sentinel ® Monitoring and Alerting System for Classification of Seizure Events.

AAN 2018

Using surface electromyography to differentiate between generalized tonic-clonic seizures and psychogenic non-epileptic seizures.

AES 2018

Surface electromyography (sEMG) burst patterns during GTC Seizures.

PAME 2018

Long-term surface electromyography (sEMG) seizure monitoring in home: False Alarm and Event Analysis during real-world use.

2017 POSTER PRESENTATIONS

AAN 2017

Application of sEMG Feature Extraction from EEG Recordings for Evaluation of Generalized Tonic-Clonic Seizure Semiology.

AAN 2017

Use of sEMG to inform GTC seizure semiology.

AES 2017

Using surface electromyography to differentiate between generalized tonic-clonic seizures and psychogenic non-epileptic seizures.

AES 2017

Surface EMG from the Brain Sentinel® Monitoring and Alerting System for classification of seizure events.

AES 2017

Using post-processed surface EMG from the Brain Sentinel® Monitoring and Alerting System for classification of GTCS and PNES, and recognition of false alarms.

ICTALS 2017

Using surface electromyography to differentiate between generalized tonic-clonic seizures and psychogenic non-epileptic seizures.

2016 POSTER PRESENTATIONS

AAN 2016

A pivotal, phase III trial of detecting generalized tonic-clonic seizures with a seizure detection and warning system.

AES 2016

Application of sEMG feature extraction from EEG recordings for evaluation of generalized tonic-clinic seizure semiology.

AES 2016

Semiology. Semiological characteristics of generalized tonic-clonic seizures assessed with video-EEG and sEMG.

2015 POSTER PRESENTATIONS

AAN 2015

Novel ambulatory EMG-based GTC seizure detection device for home and hospital use.

ACNS 2015

Automated EMG based seizure detection and quantification for the home and the EMU, a prospective multi center study.

AES 2015

Automated sEMG based seizure detection and quantification for the home and the epilepsy monitoring unit: a prospective multi center study.

ILAE 2015

Automated sEMG based seizure detection and quantification for the home and the epilepsy monitoring unit: A prospective multi center study.

ILAE 2015

BrainSentinel-Novel ambulatory EMG-based GTC seizure detection device for home and hospital use.

2014 POSTER PRESENTATIONS

AES 2014

Automated EMG based seizure detection and quantification for the home and the EMU, a prospective multi center study.

2013 POSTER PRESENTATIONS

AES 2013

EMG-based seizure detector: interim results comparing a generalized tonic-clonic seizure detection algorithm to video-EEG recordings.

sEMG Published Clinical Research

    1. Beniczky S, Conradsen I, Henning O, Fabricius M, Wolf P. Automated real-time detection of tonic-clonic seizures using a wearable EMG device. Neurology 2018;90:e428-e434. Click to view the full article

    2. Beniczky, 2016. Quantitative analysis of surface electromyography: Biomarkers for convulsive seizures.

    3. Beniczky, 2014. Quantitative analysis of surface electromyography during epileptic and nonepileptic convulsive seizures.

    4. Conradsen, 2011. Patterns of muscle activation during generalized tonic-clinic epileptic seizures.